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Using two separate drugs to lose weight naturally can be very effective you will find combinations as you're watching FDA now awaiting approval. When dealing with weight-loss and the those who go through it you ought to err on the side of caution and allow FDA do its job and demand some research be done so that the public is aware of the side effects and hazards of the medications before we drive them. Keep in mind that drug companies are in business to generate money and that they would say almost anything to keep people on their own medications. Researchers found out that participants investing in this drug for any year, lost excess weight within one month and have kept the weight off through the 56 weeks with the study. Contrave can be a combination of the drugs naltrexone and bupropion, which generally seems to reflect a whole new trend of weight-loss drugs which might be made up of more than one active ingredient, that might make them more potent and safer. Combo-pilling could be the newest fad or also the newest to come under scrutiny and for that reason it is just more publicly known although in the past, comb-pilling for weight reduction has been around since the eighties. The biggest reason that using a combination of pills has become popular will be the fact that since right now there aren't long term prescription diet pills that have been approved by the FDA other than orlistat. The truly disturbing part is doctors are prescribing these combinations of medications and some of the combinations are already rejected or have yet to be authorized by the FDA. Seizures can be a side effect with Contrave and must not be taken in individuals with seizure disorders. The drug could also raise blood pressure levels and heart rate, and really should not be used in those with a history of heart attack or stroke in the earlier six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise blood pressure and pulse rate and must 't be used in patients with uncontrolled high blood pressure, along with by a person with heart-related and cerebrovascular (circulatory dysfunction impacting the brain) disease. Patients which has a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes having a boxed warning to alert medical professionals and patients towards the increased chance of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for quitting smoking. The most common side effects reported with Contrave include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea.